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Weight loss with Tesofensine was primarily fat mass, with a notable preservation of lean mass as assessed by DEXA. Astrup et al., The Lancet May Improve Training Drive and Mood Elevated dopamine and norepinephrine levels can enhance motivation , focus , and mental resilience during challenging cutting phases

Across the six published trials, the most common adverse events were headache, mild gastrointestinal effects (diarrhea, flatulence, nausea), nasopharyngitis, fatigue, dizziness, and mild injection-site reactions

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Besides their nutritional function, peptides also fulfil a variety of other physiological roles, including some functions of the immune system, act as neurotransmitters, cell-to-cell signalling, and functions in growth and development