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Immunoblotting Total protein was extracted from 5 10 5 macrophages and quantified with the Bradford assay (Bio-Rad)

Here is the articles central honest tension, and it deserves to be stated plainly rather than smoothed over

By altering the secretory profile of senescent cells, senomorphics can mitigate tissue inflammation and promote a microenvironment more conducive to regeneration, while preserving the beneficial growth-arrest functions of senescence

An increasing number of studies suggest that the expression of SLC7A11 is finely regulated at the transcription level by transcription factors, at the post-transcription level by RNA binding proteins or noncoding RNAs, and at the protein degradation level by proteasome [59, 65,66,67,68,69,70,71,72,73]