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What they are is *relatively* harmless compared to lit tobacco, which is not only a perfectly valid piece of objective assessment based on the evidence we have, and the materials science we know extremely well (although in a slightly backhanded way e-cigarette use long term might be like losing the tips of all your fingers, whereas smoking is like being run over a series of articulated lorries, that are on fire, such is the massive harm smoking does) but that relative harm *is* the actual important point

This is certainly the most artificial of the four techniques, allowing most control over the process, and as such is highly suited to curing Bright Yellow tobacco, which is initially cured using direct fire and charcoal, but is considered today as flue-cured

Ammonia is also used for the purification of water and in the manufacturing of plastic, pesticides, explosives, dyes and other chemicals