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A B12 anemic model in immunocompromised and immunocompetent mice, demonstrates improved survival, and lower bacteria in organs, in B12 anemic animals infected with Mtb relative to non-anemic controls

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Thus, another aspect for future research of Se at the brain barriers may be related to improving our understanding on sex-related differences, including the effects of dietary Se, selenoproteins, and selenometabolites on permeability and function of BBB, BCB as well as gut-brain axis and brain immunity

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