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Chronic stress followed by social isolation promotes depressive-like behaviour, alters microglial and astrocyte biology and reduces hippocampal neurogenesis in male mice

In addition, the emergence and dissemination of resistant bacterial strains are compounded by the practice of uncontrolled using antibiotics as growth promoters to increase poultry production (Oliver et al., 2011)

Within the vascular system, oxidized low-density lipoprotein enhances superoxide generation through multiple pathways, including the induction of uncoupled endothelial NOS, activation of NADPH oxidase and xanthine oxidase enzymes, and disruption of mitochondrial electron transport chain function [139]

In fact, HTX absorption is rapid, and several factors determine HTX penetration into the CNS, including its low molecular weight, passive transport, active transport mediated by monocarboxylic acid and sodium-dependent transporters, and the lipophilicity or polarity of its metabolites [56,61] (Figure 2)