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SKU: 39012649487
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doi: 10.3390/cells8020089 135 MacintoshRLRyanKM

While BIO89-100 has been reported to be a balanced agonist of FGF21s receptors in vitro , the smaller magnitude of effect on adiponectin compared to efruxifermin suggest that BIO89-100 may not have maximally stimulated FGFR1c signaling in adipose tissue at the doses tested in humans ( Figure 3B )

In addition to arachidonic acid metabolites, several other mediators drive the recruitment of polymorphonuclear cells during acute bacterial infections