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Regulation of gut microbiota and serum neurotransmitters in mice by Streptococcus thermophilus GA8- and Lacticaseibacillus rhamnosus HAO9-fermented milk containing high levels of gamma-aminobutyric acid

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Our mechanistic findings can provide a rational approach for developing cancer treatments through targeting the ASXL1-BRD4 interaction with small molecule inhibitors, because the cancer-specific truncation variants of ASXL1 but not full-length ASXL1 have previously been shown to appreciably interact with BRD4 and induce myeloid malignancies in animal models 6,26,39