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Isoliquiritigenin (ISL), a type of flavonoid, has many health benefits but has poor bioavailability and stability and limits its application in clinical studies

One mechanism which could lead to these properties was suggested to be the binding of beta-3-adrenergic receptors located on white fat and thus increasing the rate of metabolism in fat cells

Thus, we propose QMP engineering as a strategy to ensure a long plasma half-life and enhanced therapeutic efficacy of albumin fusion proteins despite C-terminal cleavage

The UPR is comprised of three major branches: inositol requiring enzyme 1, protein kinase R-like kinase, and activated transcription factor 6