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This sustained decline culminates in severe, long-lasting consequences for both overall health and the quality of life (6)

Nat Chem Biol 5:7213

Early indications suggest that administering Lactobacillus casei strain Shirota daily for two months may significantly lessen anxiety and restore eubiosis in ME/CFS patients [91]

For example, reduced hippocampal BDNF expressiona hallmark of ethanols neurotoxicity in rodentshas been corroborated in humans, with chronic drinkers showing 50% lower BDNF levels compared to controls