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Several transcription factors such as activator protein (AP-1), nuclear factor kappa B (NF-B), and predominantly the nuclear factor erythroid 2related factor 2 (Nrf2) are involved in the induction of antioxidant enzymes

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Although the redox dependent control of these TGA is not fully established, ROXY/TGA interactions are occurring in the nucleus and affect TGA-regulated gene expression (Xing et al., 2005