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Eligible patients had at least two moderate exacerbations or one severe exacerbation in the previous year despite their use of standard inhaled therapy with corticosteroids and bronchodilators

In the case of severe vitamin B12 deficiency, consider discussing with your physician whether vitamin B12 injections can be an appropriate option

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Update: Our readers suffer from pernicious anemia and need lifelong B12 shots, so we partnered up with a lab in the UK to offer vials of medical-grade methylcobalamin for $129 or less, which can bring the cost per shot down to $3.10-$3.90