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Meanwhile, the GH-IGF1 signaling involved in DNA damage response (DDR) and DNA damage repair determines the radio-resistance of cancer cells subjected to radiotherapy and repair of adjacent tissues damaged by radiotherapy

Miller HK, Salser JS, Balis ME

Side Effects : Mild diarrhoea, Nausea, Headache, Dizziness Injection site reactions (pain, redness, swelling) Itching or rash (rare) Severe allergic reactions (anaphylaxis) (rare) Caution: Not to be used in individuals with known hypersensitivity to Vitamin B12 or cobalt

Neither compound has FDA approval or a completed human efficacy trial, so any comparison should be read as mechanism-to-mechanism, not outcome-to-outcome