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Suzuki K., Matsumoto M., Katoh Y., Liu L., Ochiai K., Aizawa Y., Nagatomi R., Okuno H., Itoi E., Igarashi K., PLoS One 2020, 15, e0236781

Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy

By the negative crosstalk between WNT and PPAR, lithium administration, by inhibiting the GSK-3 could act as a PPAR antagonist and lead to an increase in the WNT pathway, resulting in diminution of oxidative stress