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Indeed, restoring the FMRP-CYFIP1 deficiency via a small chimeric peptide acting on the dysregulation of protein synthesis could be central for the new FXS pharmacological therapy development

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We saw some improvement in disease severity but not enough to justify the risks for most patients. While the study showed that most patients should not undergo the procedure, the data hint that the benefits may outweigh the risks in some patients, such as those with exceptionally large clots

On the other hand, clinical hypothyroidism is considered a risk factor of insulin resistance, which may lead to the development of DM2