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To fully explore the potential health benets of durian fruit pulp extract as a functional supplement and to investigate the long-term eects of -EC as a potential neuroprotective biomarker, further invivo studies, including animal and human trials, are recommended

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KD treatment in patients with DKD resulted in more significant reductions in waist circumference, lean body mass, eGFR, as well as levels of insulin, HbA1c, fasting blood glucose, LDL-C, and IL-6 compared to those following a low-protein, low-salt diet, with modest increases in HDL-C and LDL-C levels [121]