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Stop using Wegovy and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without nausea or vomiting

Why this trial matters: First triple hormone receptor agonist showing major Phase III weight-loss efficacy Delivers weight-loss outcomes far beyond many current therapies Suggests a potential new metabolic and obesity care benchmark Semaglutide Shows Consistent Liver Benefits in MASH In the Phase III ESSENCE study, once-weekly semaglutide 2.4 mg significantly increased rates of steatohepatitis resolution and fibrosis improvement on liver biopsy in adults with metabolic dysfunction-associated steatohepatitis (MASH), compared with placebo

Certain factors may put you at increased risk for B12 deficiencyincluding a vegetarian or vegan diet, specific medical conditions (such as Crohns or celiac disease, or a history of gastric surgery), and age over 50

If after a trial the nausea is debilitating and doesnt lessen, that patient might not continue therapy