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As there are many attempts to find targeted therapy to control the metastatic dissemination, we focus here the signaling pathway c-Met/HGF, which is involved in many aspects of tumorigenesis including cell dissemination and metastasis

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This finding is not surprising, given the striking association between BMI and HF risk in patients with T2D emerging from the Swedish National Diabetes Registry 88

Circulation 107:13591365 Yasumura EG, Stilhano RS, Samoto VY, Matsumoto PK, de Carvalho LP, Valero Lapchik VB, Han SW (2012) Treatment of mouse limb ischemia with an integrative hypoxia-responsive vector expressing the vascular endothelial growth factor gene