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doi: 10.1892/0891-6640(2004)18 2.0.co;2 18

Additionally, transcriptomic biomarkers such as miR-122 are being explored in early-phase trials for risk stratification and treatment monitoring [343]

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Homocysteine should therefore be interpreted within the broader context of one-carbon metabolism, nutritional status and individual genetic variation, rather than as an isolated biomarker