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In some cases, this route is used because the medicine would not work as well if taken by mouth, or because it needs to be given in a controlled amount by a healthcare professional

HAT inhibitors exhibit high specificity toward oncogenic acetyltransferase complexes such as p300/CBP and can reverse chemoresistance by restoring p53 acetylation, but their clinical translation is still in the early stages due to challenges in pharmacological optimization

Side effects from B12 supplementation are rare, but possible when receiving B12 injections

GLP-1 secretion is glucose-dependent, and beyond its insulinotropic action, it suppresses glucagon release, delays gastric emptying, and reduces appetite, making it an important regulator of energy balance