Vilchze, C
Hyperhomocysteinemia and cardiovascular disease: is the adenosinergic system the missing link
The taxonomic range for the selected organisms is: Homo sapiens The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea 2.5.1.18 catalase dismutase sod pull-down malondialdehyde carcinogenesis detoxify hepatocytes smoke isoenzymes cyp1a1 smoking case-control electrophilic epoxide aquatic wistar genotoxic insecticide chemopreventive gill hepatocarcinogenesis acetylcholinesterase polycyclic pesticide hydroperoxide thiobarbituric hepatotoxicity tbars ache albino metallothioneins cigarette benzoapyrene phenobarbital drug-metabolizing preneoplastic alt aflatoxin gssg hepatoprotective schistosoma comet carboxylesterase mussel udp-glucuronosyltransferase methylation-specific gsh-px organophosphate drug development medicine cyp2d6 biotechnology analysis Synonyms gst, glutathione s-transferase, gstm1, gstp1, gstt1, glutathione-s-transferase, glutathione transferase, gsta1, gst pi, gstm3, more glutathione S-transferase - alpha class glutathione transferase - glutathione S-alkyl transferase - - - - glutathione S-aralkyltransferase - - - - glutathione S-aryltransferase - - - - glutathione S-transferase glutathione S-transferase 2 - - glutathione S-transferase A3-3 - - glutathione S-transferase omega 1 - glutathione S-transferase P1-1 glutathione S-transferase pi - glutathione S-transferase X - - - - glutathione transferase A1-1 glutathione transferase A4-4 - - glutathione transferase M1-1 - - glutathione transferase M2-2 - - glutathione transferase omega-1 - - glutathione transferase P1-1 glutathione transferase Pi - glutathione transferase T1-1 - glutathione transferase zeta - - glutathione transferase zeta 1 - glutathione transferase Zeta 1-1 - variants glutathione transferase Zeta 1a-1a, glutathione transferase Zeta 1b-1b, glutathione transferase Zeta 1c-1c, glutathione transferase Zeta 1d-1d glutathione transferase zeta1-1 - glutathione-S-transferase - - glutathione-S-transferase pi - glutathione-transferase - GSH S-transferase - - - - kappa class glutathione transferase - - S-(hydroxyalkyl)glutathione lyase - - - - selenium-containing glutathione transferase zeta1-1 - - theta class glutathione transferase T1-1 - theta-class glutathione transferase - - additional information maleylacetoacetate isomerase, EC 5.2.1.2, bifunctional enzyme RX + glutathione = HX + R-S-glutathione active site structure and catalytic mechanism, overview O43708, Q9H4Y5, Q16772, P09211, P09210, P08263, P09488, O15217, P28161, Q03013, P46439, P78417, O60760, Q7RTV2, P21266, P0CG30 RX + glutathione = HX + R-S-glutathione aryl group transfer - - - - MetaCyc 4-hydroxy-2-nonenal detoxification, camalexin biosynthesis, gliotoxin biosynthesis, glutathione-mediated detoxification I, glutathione-mediated detoxification II, indole glucosinolate activation (intact plant cell), pentachlorophenol degradation RX:glutathione R-transferase A group of enzymes of broad specificity
The contact regions are the loop 2-2, the strand 3 and the helix 3 of one monomer and the helices 4 and 5 of the other
