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Moreover, some studies have shown that the ChaC1 protein is significantly upregulated in various adverse conditions, such as diabetes, viral infection and atherosclerosis, providing cells with the amino acid nutrients they need under stressful situations but reducing GSH levels

Randomized controlled trial of oral glutathione supplementation on body stores of glutathione PubMed Ballatori N, Krance SM, Marchan R, Hammond CL

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During the manuscript submission process, two other fluorescent probes were independently reported to monitor GSH dynamics in living cells 38,39