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While there were no statistically significant findings, measures of both left ventricular end-diastolic diameter and left ventricular fractional shortening showed changes associated with the cardiomyopathy of DMD, and these trended toward a preservation of cardiac structure in the tamoxifen-treated group

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However, chronic ethanol consumption decreased the hepatic levels of methionine and S-adenosylmethionine (SAM), while the level of S-adenosylhomocysteine (SAH) remained unaffected (Fig