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Standardizing dosages and accounting for diverse dietary patterns remain essential hurdles that future research must address through large-scale, longitudinal clinical trials

Ample of proteomics and metabolomics studies have proved the considerable lipid metabolism remodeling in the myocardium of AF patients ( 3 AR) ( 2+ -handling and cell contraction, mitochondrial biogenesis, cell growth and proliferation, and so on, thus exerting cardiovascular protection with a combination of multiple mechanisms ( via LCA, a natural and biologically active micronutrient enhancing physiological FAO through CPT1B (Figures 3, 6), can significantly reduce obesity-mediated AF propensity and the corresponding atrial remodeling (Figures 1, 2), thus better supports the efficiency of FAO promotion in the AF therapeutic approach

NZ Vet J 16:317

doi: 10.1038/SREP06234 113 EsmailyHHosseini-TabatabaeiARahimianRKhorasaniRBaeeriMBarazesh-MorganiAet al