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Pernicious anemia is a very rare autoimmune disorder that does not allow for proper vitamin B12 absorption which ultimately leads individuals to have an irreversible deficiency in this vitamin

Furthermore, a proof-of-concept in vivo study in diet-induced obese mice to test the hypothesis that the most potent inhibitor when administered systemically, would reverse obesity by causing substantial loss of body weight and adiposity without causing any observable adverse effects was conducted

How AOD-9604 Works at the Cellular Level AOD-9604 exerts its fat-reducing effects through activation of beta-3 adrenergic receptors located predominantly in adipose (fat) tissue

However, when absorption is impaired, both oral and sublingual supplementation forms can be effective