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There is clear evidence to suggest a role for OATP-mediated uptake of unbound HMCD, which we and others have shown in vitro in the absence of albumin (71, 74)

Side effects are rare, but may include mild soreness at the injection site

doi: 10.1007/s00277-012-1594-z 145 AngelucciESantiniVDi TucciAAQuaresminiGFinelliCVolpeAet al

In the early stage of cytotoxicity (upper panel), lymphocytes (identified by electron-dense nuclei and a narrow rim of cytoplasm) are closely apposed to myofibroblast-like cells (spindle-shaped with elliptical nuclei and abundant cytoplasm containing rough endoplasmic reticulum, mitochondria, and an actin belt)