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Recent studies have indicated that twelve weeks of aerobic Baduanjin training in 5565-year-old postmenopausal MAFLD women and 6 weeks of treadmill exercise in HFD-induced male C57BL/6J MAFLD mice significantly elevated patients plasma exosomal miR-324 and mices adipose miR-324 compared to controls, concurrent with reduced liver/fat weight and plasma TG, alanine aminotransferase (ALT) and aspartate aminotransferase (AST), confirming aerobic exercise upregulates miR-324 to mitigate hepatic lipid deposition

S1F upper panel), while USP2 OE increased the protein level of TGFBR1 in TECs (Fig