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Studies have shown that in a mouse model of ischemic stroke, the level of GSH in neurons is significantly decreased, the degree of lipid peroxidation is enhanced, and the activity of GPX is decreased 71

Zahreddine H, Borden KLB

Another interesting finding of this study was that adult mice (~4-months-old) displayed the largest changes after acute THC exposure compared to exposed ~1 and ~2-month-old mice, with a general downregulation of the endocannabinoid system

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