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The composition of the present invention may contain any such additional ingredients so as to provide the composition in a form suitable for administration

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After the substrates and ions enter through the opening and bind to their respective sites, extracellular loop 4 (EL4) locks the opening of the gate and the transporter shifts to the substrate occluded state

Sensorgrams were analyzed using a global fit to the 1:1 Langmuir binding model