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doi: 10.1016/j.jare.2025.02.003 55 CaequeTBaronLMllerSCarmonaAColombeauLVersiniAet al

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Decades of genome-wide linkage scans have confirmed that PSORS1 is the most significant susceptibility locus identified through familial linkage studies, accounting for up to 50% of the genetic contribution to psoriasis (Rahman and Elder 2005)