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Multiple ARG inhibitors are being developed in tumor immunotherapy

Because mold exposure alters gut microbiota and impairs mucosal immunity, these patterns may be a downstream consequence of toxicant-driven immune suppression

For instance, Akkermansia muciniphila in the gut can induce immune homeostasis in mice, promote IgG production, and initiate antigen-specific T-cell responses, thereby improving symptoms of DSS-induced colitis (92)