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doi: 10.1002/jpln.201400476 145 UlhassanZ.HuangQ.GillR

Dysbiosis is associated with the excessive production of pro-oxidant metabolites, weakened antioxidant defenses, and the release of microbial products, such as lipopolysaccharides, that activate the NF-B and inflammasome pathways [143]

Other enzyme deficiencies cause acute episodes of severe hemolysis [e.g., when oxidative stress on the red cell is increased (as in some types of glucose-6-phosphate dehydrogenase deficiency)]