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I think having a slow acting protein at bedtime makes far more sense and then getting a good nights sleep

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4.8 Undesirable effects As most undesirable effects are based on post-marketing spontaneous reporting, frequency estimation is not possible

It interacts with the following medicines: Clozapine Live attenuated vaccines and related products Fluoroquinolone antibiotic It can also interact with following disease condition: Infections Kidney disease Warning And Precaution: Alimta 100 mg Injection can worsen the conditions like: Allergy Liver/kidney disease You must use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it You must have regular blood and urine tests done to monitor your body function while you are having treatment with this medicine You must monitor your blood pressure regularly while taking this medication You should not drive or operate heavy machinery while taking this medicine as it may cause nausea and vomiting Always consult with your doctor immediately to get best possible treatment if you are suffering from any of the above mentioned conditions