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This signaling cascade promotes ERK-dependent, rather than CDK5/p25-dependent, phosphorylation and transcriptional activation of PPAR, thereby enhancing the expression of genes associated with insulin sensitivity

The regulation loop of MARVELD1 interacting with PARP1 in DNA damage response maintains genome stability and promotes therapy resistance of cancer cells

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578 A polycatechol composed of dopamine and L-Dopa can isolate the unstable iron pool, scavenge free radicals, protect mitochondria, and prevent ferroptosis, while inhibiting A and tau protein aggregation to save neuronal cell death