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Similarly to the mouse study, CD4CAR-modified HSPCs engrafted and differentiated into multiple haematopoietic lineages that expressed the CAR, including natural killer cells, which have the cellular machinery to integrate signals through the TCR CD3 chain and may contribute to HIV-specific immunity 65

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Nonobese (control) and DIO mice were randomized to undergo orthotopic transplantation with either GPX4-knockdown metM-Wnt lung cells or scramble control metM-Wnt lung cells, and then further randomized to receive treatment with either carboplatin or vehicle control (Fig

First Things First: What is Reconstitution, Really