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Most tobacco products, including e cigarettes, contain nicotine, a chemical that can harm the heart, brain and whole body. As with other addictive products, using a nicotine product builds tolerance, leading to more Frontiers Multifactorial Etiology of Adolescent Nicotine Addiction: A Review of the Neurobiology of Nicotine Addiction and Its Implications for Smoking Cessation Pharmacotherapy The 10 Most Addictive Substances on Earth Rehab Spot Smoking and Addiction The Newfoundland and Labrador Alliance for the Control of Tobacco
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