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As an NADPH-selective enzyme, FSP1 suppresses ferroptosis by oxidizing NADPH

Cytochrome P450 enzymes (CYPs) A family of enzymes that is responsible for the oxidative biotransformation of xenobiotics and other compounds

Short N, Jabbour EJ, Ravandi F, Huang X, Jain N, Sasaki K, Pemmaraju N, Daver NG, Khoury JD, Jorgensen JL, Alvarado Y, Konopleva MY, Garcia-Manero G, Kadia TM, Yilmaz M, Borthakur G , Burger JA, Kornblau SM, Wierda WG, DiNardo CD, Ferrajoli A, Nasnas P, Jacob J, Garris RE, OBrien SM, Kantarjian H

For the protein solutions the excitation wavelength was fixed at 295 nm (maximum absorbance = 0.10 OD) and emission spectra were recorded between 310 and 410 nm with an emission slit width of 2.5 nm