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In an MPTP-induced Parkinson's disease animal model, intracerebroventricular injection of PBzyme decreases dopaminergic degradation and inhibits neuroinflammation by downregulating the activation of microglial nucleotide-binding domain and leucine-rich repeat family pyrin domain containing 3 (NLRP3) inflammasomes and caspase-1 by scavenging reactive oxygen species which ultimately leads to microglia pyroptosis (Ma et al., 2022)

129 While some CT programmes have improved diet quality and empowered women, 130 receiving cash does not automatically translate into healthier diets

Understanding these preclinical findings helps researchers design informed experiments while recognizing the current limitations of translating results to other species (Pickart & Margolina, 2018)

Discussion The c-MET is a key receptor tyrosine kinase expressed predominantly in epithelial cells