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Sperm-enriched circRNAs are emerging as potential regulators of spermatogenesis and motility but remain at an exploratory stage with limited clinical endpoint data [156]

Red or purple chromaturia is a side effect of hydroxocobalamin, typically resolving over several weeks.2 Additional causes of red urine include blood (e.g., traumatic catheterization, malignancy, infection), dietary ingestion (e.g., beets), and medications (e.g., rifampin, phenothiazines).3 Although benign and not warranting further evaluation by itself, hydroxocobalamin-induced discolouration of body fluids may interfere with colorimetric sensors

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consequently, they are contraindicated in the treatment of cocaine-associated ischemia