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Yes, Folic Acid and B12 are often taken daily as part of a balanced supplement regimen

doi:10.1053/j.tcam.2017.10.003

Antispasmodics (e.g., hyoscyamine) and peppermint oil alleviate abnormal contractions but lack robust evidence in constipation-related pain, while laxatives improve stool passage but show limited direct analgesic efficacy

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