Furthermore, both preterm and term infants exhibit decreased activity and expression of the placental physiological barrier 11-HSD2 (278281), consistent with the proposed increased cortisol bioavailability
As discussed above, arsenic interacts with protein-SH groups and inhibits the activity of glutathione (GSH), which increases the level of oxidative stress manifested by increased oxidative damage in mouse and human skin
Disclosures: Cara Mack: Nothing to Disclose, Yuhuan Luo: Nothing to Disclose, Julia Jezykowski: Nothing to Disclose, Lisa Fraser: Nothing to Disclose, Nitika Gupta: Nothing to Disclose, Alexander Miethke: Mirum Pharmaceutical Inc: Grant/Research Support, Mirum Pharmaceutical Inc: Consultant, Ipsen: Speaking and Teaching, Sarah Taylor: Mirum Pharmaceuticals: Consultant, Ipsen Pharmaceutical: Consultant, Mirum Pharmaceutical: Consultant, Estella Alonso: Nothing to Disclose, Simon Horslen: Nothing to Disclose, Rohit Kohli: Mirum: Consultant, Ipsen: Consultant, Epigen: Grant/Research Support, Sanofi Rare Disease: Consultant, Jean Molleston: Gillead: Grant/Research Support, Albireo: Grant/Research Support, Abbvie: Grant/Research Support, Mirum/Shire: Grant/Research Support, CF FOundation: Grant/Research Support, Binita Kamath: Mirum: Consultant, Mirum: Grant/Research Support, Albireo/Ipsen: Consultant, Albireo/Ipsen: Grant/Research Support, Audentes: Consultant, Stephen Guthery: Nothing to Disclose, Kathleen Loomes: Mirum: Consultant, Albireo/Ipsen: Consultant, Mirum: Clinical trials, Albireo/Ipsen: Clinical trials, John Magee: Nothing to Disclose, Philip Rosenthal: Nothing to Disclose, Pamela Valentino: Grifols: Advisor, Mirum: Speaking and Teaching, Ronald Sokol: Nothing to Disclose 2477 EXTRACELLULAR VESICLE MIRNA ANALYSIS FROM ADOLESCENTS WITH MASLD WITH AND WITHOUT OBSTRUCTIVE SLEEP APNEA/CHRONIC INTERMITTENT HYPOXIA Shikha Sundaram 1 Swati Ghosh 1 Alexander Chaidez 1 Ronald Sokol 2 , 1 Children's Hospital Colorado, 2 University of Colorado School of Medicine Background: Metabolic Associated Steatotic Liver Disease (MASLD) is the predominant cause of chronic liver disease in children
doi: 10.1093/ajcn/88.4.894 13 CortezR
