Females of childbearing potential must use two reliable forms of contraception simultaneously during oral tretinoin therapy and for one month following discontinuation of therapy, unless abstinence is the chosen method
Nicotinamide and allopurinol seem to be effective in reducing the inflammation of soft tissue but the data sustaining this conclusion were obtained in a rather small sample of GO patients affected with both moderate-to-severe and mild GO ( in vitro results on the use of pentoxifylline are promising, but clinical studies provided conflicting results ( in vitro findings reported above, one can speculate that quercetin and -carotene might be the most promising, but clinical trials are needed to confirm this hypothesis

The Ordinary Best topical additive Photo by Innerbody Research Pros Extremely well priced Also contains 3% ferulic acid One bottle can last several months Mixes well with various moisturizers Doesnt add an oiliness or smell Uses propanediol instead of propylene glycol One-year return policy Cons No markings on the dropper Cant predict efficacy across various carrier products (i.e., your preferred moisturizer) One bottle is too inexpensive to qualify for free shipping ($4.99 otherwise) A 2019 review of resveratrols potential for cosmetic uses describes anti-aging and anti-inflammatory properties, including skin whitening, protection from UVB and UVA rays, and increased firmness and elasticity after 12 weeks of topical application to the face.24 Several resveratrol-based cosmetic products might help you see these benefits, but switching to one of them might throw off the regimen you've perfected for your unique skin

Many experts suggest taking glutathione on an empty stomach or a few hours after a meal to enhance its bioavailability