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Querido, J

Relevance of 4-F 4t -neuroprostane and 10-F 4t -neuroprostane to neurological diseases

37,38 In some MDD patients, stress leads to long-term elevated glucocorticoids, resulting in synaptic structural changes and remodeling, and the stress-induced hyperactivity of the HPA axis leads to negative feedback imbalance of the HPA axis, which is also related to depression

Additionally, the buffers used for the affinity purification reactions should have an appropriate pH and ionic strength to promote binding between the immobilized ligand and target