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Psychiatry 145 PonzettoC.BardelliA.ZhenZ.MainaF.dalla ZoncaP.GiordanoS.et al (1994)

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For example, if your supplement happens to be 10 g, then cutting it in half and taking the resulting 5 g supplement twice a day (at least 4 hours apart) will meet the EFSA recommendations

Damage to the lining of the stomach and small intestine results in symptoms that range from relatively minor heartburn, nausea, and abdominal pain (affecting 15-40% of NSAID users) to the life-threatening ulceration, perforation, and bleeding (affecting 1-2% of chronic NSAID users) (Vonkeman 2010)