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Flavonolignans are the major bioactive components presented in the Milk thistle ( Silybum marianum ) mostly known for their hepatoprotective properties, but also standing out for their immunomodulatory, antioxidant, and antitumoral role [571]

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These charged particles tend to combine to form radicals, which contribute to creating oxidative stress in the brain, which can damage brain cells, or neurons, resulting in their death