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Researchers who travel frequently should review the guidance on room temperature peptide stability to understand exactly how much potency they risk during transit

Jerant AF, Johnson JT, Sheridan CD, Caffrey TJ

Specifically, when permeability (as measured by the cell ratio, defined as the cellular EC 50 / Mdm2 K D ), was plotted versus peptide helicity, we noted that peptides with poor cell ratios (400 or greater) also had low helicity values ( 3) was not a practical path to the clinic as these molecules also displayed poor solubilities (often 10x loss in cellular potency when tested in the presence of 10% FBS (Supplementary Table 3)