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The combination of a PRMT5 inhibitor and anti-PD1 therapy produced a significant reduction in tumour volume and an increase in CD4+ and CD8+ T cell infiltration compared to either therapy alone in vivo (45)

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Int J Mol Sci 20:2158 Thi VLD, Wu X, Rice CM (2019) Stem cellderived culture models of hepatitis e virus infection

The skin parameters were measured by corneometer (hydration), tewameter (TEWL), an Antera 3D system (wrinkles), and elasticity (cutometer) at baseline and day 42 and day 84 in the treatment groups ( n = 36 treatment