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For example, the release of interleukin-1 in murine rectal cancer models caused the differentiation of tumor-associated fibroblasts into more pro-tumorigenic fibroblasts and reduced the anti-tumor effect of radiotherapy (107)

Patients improved on both sensation tests and neuropathy scores, and no side effects were reported (Ebadi et al., 2023)

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[DOI] [Google Scholar] 32.Cappellini M.D., Comin-Colet J., de Francisco A., Dignass A., Doehner W., Lam C.S., Macdougall I.C., Rogler G., Camaschella C., Kadir R., et al