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Ailanthone triggers autophagic degradation of methyltransferase KMT2A, which induces reduced H3K9me1 on the promoter region of PHGDH

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These findings suggest melatonin enhances the antioxidant response and supports mitochondrial function under oxidative stress

Adopting a functional medicine approach, which emphasizes personalized care, nutrition, and lifestyle changes, helps manage AMD and slow its progression