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Other B Complex Side Effects and When to See a Doctor Outside of stool changes, you may experience other side effects when taking B complex supplements, including: Diarrhea Facial redness Extreme tiredness Headache Nausea Upset stomach Bright yellow pee However, unless these are persistent or interfere with daily life, you may not need to see a healthcare professional if you experience these effects

The Role of Vascular Endothelial Growth Factor in the Hypoxic and Immunosuppressive Tumor Microenvironment: Perspectives for Therapeutic Implications

With those caveats in mind, here's what the published data shows at each stage

Disulfiram does not reduce cravings, but instead deters drinking by making it physically unpleasant