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Oncotarget 12, 23232337

The study enrolled people who met the following criteria: Documented SARS-CoV-2 infection confirmed by PCR at least two months before joining the study, but not currently infected Persistent cognitive difficulties (brain fog) beginning around the time of infection At least two ongoing neurological or physical symptoms since COVID-19 infection, such as fatigue, weakness, headache, loss of smell, tingling or numbness, shortness of breath, loss of appetite, heart palpitations or tachycardia, hair loss, musculoskeletal pain, or chest pain Not pregnant or lactating A key finding from this trial was that NR supplementation effectively increased whole blood NAD+ levels and was associated with improvements in participants executive functioning, sleep quality, and self-reported fatigue and mood compared to their own baselines

"Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism." Ann NY Acad Sci 2004;1033:30-41